Is Tamoxifen Effective In Curing Breast Cancer?
Is Tamoxifen Effective In Curing Breast Cancer? By Camry James
Tamoxifen, known in the trade as Nolvadex, is usually prescribed by specialists in and is taken in pill form. A patient will stay on the drug for about five years.
Often the woman's cancer will be tested to see if it is sensitive to the amount of oestrogen in the system. If the cancer is oestrogen sensitive, tamoxifen will be given.
Because tamoxifen is such a weak estrogen, its estrogen signals don't stimulate very much cell growth. And because it has stolen the place away from more powerful estrogen, it blocks estrogen-stimulated cancer cell growth. In this way, tamoxifen acts like an "anti-estrogen."
Tamoxifen may also take the place of natural estrogen in the receptors of healthy breast cells. In that way it holds down growth activity, and possibly stops abnormal growth and the development of a totally new breast cancer. By blocking natural estrogen from getting to the receptors, tamoxifen is helpful in reducing the risk of in women at high risk who have never had breast cancer. It also can help women who have already had in one breast by lowering the risk of a new forming in the other breast.
One study found that radiation plus tamoxifen was much better than tamoxifen alone at reducing the risk of breast cancer coming back after a lumpectomy in women with hormone-receptor-positive breast cancer. This was true even for women with very small cancers.
For pre-menopausal women,
Scientists find a gene that makes cancer spread (Reuters) Reuters - A single gene appears to play a crucial role in deadly breast cancers, increasing the chances the cancer will spread and making it resistant to chemotherapy, U.S. researchers said on Monday. Diet tied to survival in breast cancer patients (Reuters) Reuters - Women with early-stage breast cancer may live longer if they maintain a diet rich in fruits, vegetables, whole grains and low-fat dairy, a new study suggests. Genes Predict Chances of Breast Cancer's Spread (HealthDay) HealthDay - THURSDAY, Jan. 1 (HealthDay News) -- In a finding that could help
doctors fine-tune breast cancer treatments even further, a new study
confirms that there are genes that increase the likelihood that the
disease will spread throughout a woman's body. High Insulin May Boost Odds of Breast Cancer (HealthDay) HealthDay - TUESDAY, Dec. 30 (HealthDay News) -- Women with high levels of insulin
in their blood appear to be more likely to develop breast cancer than
those with lower insulin levels. High insulin levels may increase breast cancer risk (Reuters) Reuters - Data from the Women's Health Initiative Observational Study show that higher than normal insulin levels are an independent risk factor for breast cancer. Trying to prevent lymphedema after breast cancer (AP) AP - Hospitals in about a dozen states are testing whether some simple steps, such as arm-strengthening exercises, could reduce the risk of one of breast cancer's troubling legacies — the painful and sometimes severe arm swelling called lymphedema. Lymphedema has long been a neglected side effect of cancer surgery and radiation: Many women say they never were warned, even though spotting this problem early improves outcomes. Cancer Medicine Advances on Many Fronts (HealthDay) HealthDay - TUESDAY, Dec. 23 (HealthDay News) -- The war against cancer gathered
steam in 2008, as new drugs tackled the toughest cancers with some
success, and advances were made in both disease prevention and risk factor
identification. British woman to deliver baby screened for breast cancer (AFP) AFP - A woman is to give birth this week to the first baby in Britain which has been selected to be free of a gene which greatly increases the risk of breast cancer, experts said. Obesity raises risk of cancer-related lymphedema (Reuters) Reuters - Painful swelling of the arm or shoulder area following treatment for breast cancer -- a condition called lymphedema - is more common in women who are overweight or obese than in women of normal weight, researchers have found. Marital Distress May Affect Breast Cancer Recovery (HealthDay) HealthDay - THURSDAY, Dec. 18 (HealthDay News) -- Marriage problems are
associated with poorer outcomes for women with breast cancer, a new U.S.
study finds.
tamoxifen is the best hormonal therapy. But tamoxifen is no longer the first choice for post-menopausal women. If you've been on tamoxifen for two to three years and now you're in menopause, your doctor may recommend that you switch to an aromatase inhibitor to finish your five years of hormonal therapy. However, you can still get a lot of benefit if you take tamoxifen for up to five years and then switch to an aromatase inhibitor.
Tamoxifen was first used to fight at the Christie Hospital in Manchester, England, in 1969. It has since proved its worth as means of stopping the spread or recurrence of the disease in women who have already been treated for it.
But, it was noticed back in the early 1980s that some women who were receiving the drug for cancer in one breast did not develop any tumorous growth in the other. This prompted the suggestion that Tamoxifen might have another preventative role for those women who are at risk of getting but have yet to develop any signs of the disease.
About the Author: Tamoxifen has been proven to be the cure to Breast Cancer. We urge you to find out more about Tamoxifen at http://Tamoxifen.eask.info
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